Is it necessary to use power isolation and digital interface isolation for increase the sensitivity?

Question

Is it necessary to use power isolation and digital interface (i2c, spi) isolation for increase the sensitivity of the analog part of the receiver of the radio communication systems?

PKusior · Accepted Answer

On behalf of David Carr: Isolation is sometimes used to separate noisy circuitry from more sensitive analog or RF circuits. It may be beneficial if you’re experiencing performance issues due to noise, but I wouldn’t say it’s absolutely necessary. I hope that’s helpful.)

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Is it necessary to use power isolation and digital interface isolation for increase the sensitivity?