ADR444 reference design for noise reduction?

We need reference voltage of 4,096V with the lowest noise.

We try ADR444 + output filter+pA low noise buffer amplifier.

Before we start counting and beating a dead path, you do not have a appnote or reference design with similar problem?

For specify. We need voltage reference with 0.1-10Hz output noise ~250nVp-p

Capacity how much can hang on output ADR4xx?