I have 2 AD5241 (1MOhm) soldered by hand. The first one got maybe a bit hot but the second one should be fine.
A: 100kOhm --- GND
SCL: Master with pullup
SDA: Master with pullup
Transfered Data after slave address:
0x40 (or 0x58 for O1+O2)
0x00 (or 0xFF as test conditions)
The transfer from the Master should be correct (ACK was always sent and O1+O2 work as expected)
The problem ist the voltage drop between W and A. It is a bit above 1V in both test conditions for both AD5241.