I think that the title pretty much says it all.
With VDSP 5.0 Update 8 installed, attempts to create the VisualDSP.ADspSAFP object result in an exception and a crash (return code looks like RPC_E_SERVERFAULT, which isn't very helpful.)
Reinstalling VSDP 5.0 with no updates works. It also works with Update 7. I can provide more details if they would be helpful, but it look easily reproducible.