If use this protection IC USB Connector side (Vbus, D +, D-) input the 12V voltage
protection whether action? have this kind of protection applications IC?thanks.
The ADG4612/ADG4613 are parts with overvoltage protection and can operate with a 5V single supply.
The bandwidth of these parts may not suit your application though. The low voltage switches in our portfolio that can support USB2.0 do not have overvoltage protection.