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ADG751 Source isolation

Hello, 

I want to use ADG751 switches for a circuit I am working on. My switches in this circuit are floating (sources are not grounded), will be this a problem using ADG751 CMOS switches? Also, I am driving the gate(switch on and off in high speed around 1MHz) using a microcontroller, do I need to have an isolation for the floating source?  or I need a bootstrap circuit to ensure turning the switches on & off ?

Thanks

Jacob