Hi, cdubs,

-0.5 to 7V is from the absolute max ratings (Table15 in the ADuM4154 datasheet). Table 14 has the recommended operating conditions, which are 3.0V to 5.5V.  The ADuM4154 cannot be supplied with 2.5V. 

If the design requires a 2.5V supply, the ADuM141E…