What are the performance implications of using the ADL5206 in a single-ended input to differential output configuration, and what are the recommended options?

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There is no measurement data available that shows the performance of the ADL5206 when driven single-ended. Typically, when a differential amplifier is driven with single-ended input, the second and third order harmonic performance tends to degrade. Your options are to include an input balun in your design, such as the one used on the eval board, or drive the input single-ended with VIN- ac-coupled to ground and accept the performance impact. It is recommended to obtain an ADL5206 evaluation board, as it has the necessary hooks to drive the input differentially or single-ended.

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ADL5206 : FAQ