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ADTR1107 #12(CPLR_OUT) Pin configuration qeustion?

Category: Datasheet/Specs
Product Number: ADTR1107ACCZ

Dear Sir/Madam, 

We are reviewing the design of ADTR1107ACCZ.
Please check if pin 12 (#12(CPLR_OUT) can be used as N.C.
If I don't use it, do I need 50-Ohm Termination?

If not used, will the following characteristics of TX PATH be affected?
 - Gain
 - Input/Output Return Loss

Best & Regards,