LTC5577 Sanity Check

Are there any problems using this part with a low-side LO for sub-GHz RF?  The specs look fine but the examples (figure 1) are all high side injection for RF below 1GHz.  Any reason?

In our specific case, it's LO=854MHz RF=899MHz IF=45MHz, part=LTC5577IUF#PBF.

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