LTM8049
Recommended for New Designs
The LTM8049 is a Dual SEPIC/Inverting μModule® (power module) DC/DC Converter. Each of the two outputs can be easily configured as a SEPIC or Inverting...
Datasheet
LTM8049 on Analog.com
LTspice
Production
LTspice® is a powerful, fast, and free SPICE simulator software, schematic capture and waveform viewer with enhancements and models for improving the simulation...
LTspice on Analog.com
The LTSpice demo circuit for LTM8049 has share pins connected: https://www.analog.com/en/resources/design-tools-and-calculators/ltspice-simulator/lt-spice-demo-circuits.html 
From datasheet, this should only be done when using outputs in parallel configuration, to enable current sharing. This is not the configuration of the demo LTSpice schematic. 
Although the simulation seems to work, changing load conditions will give bad results. Removing the share net improves the simulation.
Can you confirm that for this configuration (or other dual rail configurations), the share pins should be connected or not?
Thanks in advance
You should only connect SHARE1 and SHARE2 if using the outputs in parallel. If designing for two separate supplies, leave SHARE1 and SHARE2 floating.
Hi TimW,
Thanks for your quick response. Yes this is as I thought, therefore the demo schematic should be corrected https://www.analog.com/media/en/simulation-models/LTspice-demo-circuits/LTM8049_DC2244A.asc
Yes, I've let the product line know about this. Thanks.