in Fig. 62 (Recommend Layout) the datasheet of the ADP5360 the ENSD (B3) is connected AGND2 (B2) to pull it low.
AGND2 is not connected to anything else.
Are AGND1 and AGND2 internally connected? Is the the layout depicted in the datasheet functioning?
Also: the numbering scheme in Fig. 62 appears to be reversed.