Question about PCB layout of 2 x ADP2442

Question

Hi All, 
 Two ADP2442s are mounted on our customer's PCB but they don't work normally.They stop to work during start-up. 
 I have attached the customer's schematic and layout. Both 3.3V_GND and 5V_GND are not separated on the layer 2. 
 Do you think that it could be the cause of this start-up issue? 
 Regards, 
 Kazu

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Question about PCB layout of 2 x ADP2442