Can cf-ad9361-lpc work with AD9361 in 1rx-1tx mode?

We are trying to write a small piece of code to record RF samples received by E310. The reference example code we use is ad9361-iiostream.c from the libiio/example. We setup the receiving stream channel for I and Q via device cf-ad9361-lpc. The code works well when AD9361 is in 2rx-2tx mode. However, if we change AD9361 to the 1rx-1tx mode, function iio_buffer_refill returns an error code -110. 

What might be the issue here? Thanks!

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