How to use the LTC4317 I2C address translator?

I have an embedded board that has 2 separate I2C bus connections.  The I2C slave devices have a fixed address of 0x52, so I'm restricted to only 2 instances right now, but I would like to support up to 4.  I know I will have to make Linux driver changes to support the translated addresses, but I need advice on how to wire it up.

The I2C slave devices are Nintendo Classic controllers and have a 6-pin pinout shown here.

My questions for the LTC4317:

  1. What are the READY# and ENABLE# pins for?
  2. Do I wire up the device's 3.3V to the READY# pin?