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ADuM5210 product question

I am looking at using the ADuM5210 for voltage and communication isolation.

On page 4 of the datasheet, it says that the Logic High Input Threshold is .7 Viso, .7 VDD1.

Is this listed because the input signals could be from either the left or right sides?

Looking at page 14, it says that Vdd1 is the power supply for Side 1 of the logic circuits and is independent from Vddp. If we are looking to use the 5210 package, will we also need voltage on Vdd2 to produce an output, and does Vdd2 need to be isolated if we require an isolated output communication

In addition, I am looking to have VDDP set to 5 Volts such that VISO is 5 Volts, if I understand correctly Vdd1 and Vdd2 could use lower voltage levels? Looking at page 19 for the schematic, is it recommended not to have Vdd1 and Vdd2 connected together? If Vdd2 does require a voltage, I am looking to power both Vdd1 and Vdd2 from the same supply.

Just trying to understand the device a bit better.

Best Regards.