Different Voltage at A and B side of the isolation

Question

Hi Team, 
 We are using ADuM250N digital isolator in the design. From datasheet, this IC is capable of driving at 1.8V, 2.5V, 3.3V and 5V at both Vdd1 and Vdd2. Can you please confirm whether I can use Vdd1=3.3V and Vdd2=1.8V or viceversa? Is there any challenges? 
 Regards, 
 Raghul

jnaso · Accepted Answer

Hi Raghul, 
 Its fine to operate with mixed supplies. The two sides of the isolator are independent. The logic levels of the inputs and outputs will scale to the local VDD pin voltage. 
 Regards, 
 Jason)

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Different Voltage at A and B side of the isolation