Can a ADuM1250 be used to isolate a 5V GPIO?

Hi,

Because the GPIO can use S/W programming input or output,
so need support bidirectional isolator.
Can a ADuM1250 be used to isolator a digital interface 5V GPIO?
or ADuM1250 support I2C interface only?

And ADuM1250 side2 output current driving is 100mA,right?