SigmaStudio 4.1 crashes on startup in Windows 10, but runs in Safe Mode


I have just installed SigmaStudio 4.1 64bits in my windows 10 machine, but when trying t start the program it crashes

I tried running it in compatibility mode on windows xp, 7 and 8, without success.

I tried running it on Safe Mode and the program did start correctly, how can I solve this?