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How to divide the frame operation on 21489

The official routine 21489-I2S C Sampled-Based Talkthru is to process the signal point by point, how to change it into frame processing, for example, 10 points are used as a frame, and some operation is performed every 10 points.It is necessary to ensure that this operation is carried out within 10 points of time without being interruptedAnother question is that the sampling frequency in this routine is 48khz, how to change it to 16khz