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The AD5422 has a feature whereby, when the external RSET is being used, the “REXT” bit (D13 in Control Register), should only be set in the same write command as “OUTEN” bit (D12 in Control Register) gets set.
Alternately, "REXT" bit can be set before the "OUTEN" bit is set, but the range bits (D2:D0 in Control Register) must be changed on the write in which the output is enabled. See figure below for best practice.