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Three electrode measurement for AD5933?

Thread Summary

The user is using the AD5933 for bioelectrical electrode impedance measurements in a three-electrode configuration. The issue was discontinuities in the Nyquist plot and large errors at low frequencies. The solution involved recalculating the MCLK for each frequency, ensuring the excitation signal was within the ADC range, and adjusting the high-pass filter cutoff frequency to 0.14 Hz. This resulted in continuous and more accurate impedance measurements.
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Hi everybody,

 

we're using the AD5933 for bioelectrical electrode impedance measurements. Usually, the electrodes have to be immersed in a saline solution for measuring, and a 2 point measurement (Electrode to Reference electrode) adds unwanted potential offsets to the measurement. For a more accurate measurement, a technique using 3 electrodes is employed:

 

(Fig. 4 from this link)

Ralph Group : projects : Fabrication and characterization of graphene electrodes for electrochemistry experiments

Figure 4

Is there any way to connect the AD5933 in such an arrangement to measure impedance? Do you have any additional suggestions for performing such a measurement?

 

Thanks and Kindest Regards,

Oscar Cota

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  • Hi everybody,

    I add some extra info I have researched to see if somebody could help us. Here's one schematic of what the lab equipment does to measure electrode impedance. There is a stimulation voltage Vin that generates a current i, which is measured at a TIA. However, Vin is not directly applied to the electrode, but to a control loop that ensures that Vref=Vin. Therefore, Vin is between Vref and Virtual GND (working electrode). The impedance contribution of the counter electrode is thus eliminated.

    (Source: E760 - Lectures on Electrodes I - Martin Schüttler . University College London 2009)

    Do you think such arrangement is feasible with the AD5933?

    Cheers and Kind Regards,

    Oscar

Reply
  • Hi everybody,

    I add some extra info I have researched to see if somebody could help us. Here's one schematic of what the lab equipment does to measure electrode impedance. There is a stimulation voltage Vin that generates a current i, which is measured at a TIA. However, Vin is not directly applied to the electrode, but to a control loop that ensures that Vref=Vin. Therefore, Vin is between Vref and Virtual GND (working electrode). The impedance contribution of the counter electrode is thus eliminated.

    (Source: E760 - Lectures on Electrodes I - Martin Schüttler . University College London 2009)

    Do you think such arrangement is feasible with the AD5933?

    Cheers and Kind Regards,

    Oscar

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