ADuC7060 Vref question

I am feeding the analog input with an instrumentation amp the outputs .160Vdc to 1.9Vdc.  I am currently using the external reference vref+ = 2.5Vdc and vref- = gnd.  If I put .160Vdc on vref- and 2Vdc on vref+ will that allow me to use the full range of ADC counts?