I am FAE in Japanese distributor.
Our customer will evaluate EVAL-AD8494.
UG1421 mentions EVAL-AD8494 needs both +5V and -5V.
AD8494 works at single 5V supply.
Can EVAL-AD8494 work at single 5V supply?
Yes the EVAL-AD8494 can work at single 5V supply. Just connect the GND and -VS header pin in P_SUPPLY together for a single supply configuration. However, if you want to measure a negative temperature in a single supply configuration, a positive voltage less than +VS should be applied to the reference pin to shift the output. Remove the jumper from J2 so that the reference pin is not grounded.
You can view more details regarding this on the user guide.