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Designing circuit inputs for high voltage

I am building a device where my customers hook up their own sensors.   Your instrumentation amplifier is the first component in my signal chain. Sometimes my customers make a mistake and connect the inputs to the wrong thing.  When this happens, the instrumentation amplifier in the circuit can be subjected to a large voltage.  My circuit needs to be robust and be able to handle this large voltage without damage.  How can I design my circuit not to be damaged in this overvoltage condition?

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