The datasheet for the ADA4841 says that the exposed paddle of the LFCSP package should be connected to ground (Figure 3 on first page). In a split supply design is that Ground (0V) or is it the negative supply?
The question is what you consider GND. Is GND the negative supply or the system GND. For example, if I have +Vs (Pin 8) connected to +5V and -Vs (Pin 4) connected to -5V, is the exposed pad connected to 0V or to -5V?