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Latch up AD8646


i am using AD8646 for voltage follower as illustrated in following schematic. the output of AD8646 shall be connected to 12Bit ADC for voltage measurement UDC (range 0 to 820V). The supply of AD8646 is V2 (4,5V), which can be manually turned off and on; or permanently off. This is my issue because during the power cycle of V2, the UDC could still present and with the voltage divider, 3V is present at the (+) input of ADC8646. The sum of current (flows on R1) is relatively low at 300uA.

Could this condition triggers latch up on AD8646? is there any other damage that could occurs?

many thx and best regards,